Published Scientific Journal Articles about Pomegranates

We have compiled a list of independent scientific research being done internationally investigating the health benefits of the pomegranate. It is only a partial list of the broad range of research efforts worldwide. This section is intended as a general reference.

Note: Abstracts and full text articles can be found at www.pubmed.gov.

Partial identification of bioactive compounds having antifungal activities from Punica granatum peel extracts. Glazer I, Masaphy S, Marciano P, Bar-Ilan I, Holland D, Kerem Z, Amir R. J Agric Food Chem. 2012 Apr 25. [Epub ahead of print]

Antidiabetic and antihyperlipidemic effects of ethanolic extract of leaves of Punica granatum in alloxan-induced non-insulin-dependent diabetes mellitus albino rats. Das S, Barman S. Indian J Pharmacol. 2012 Mar;44(2):219-24.

Genome Sequence of Xanthomonas axonopodis pv. punicae Strain LMG 859. Sharma V, Midha S, Ranjan M, Pinnaka AK, Patil PB. J Bacteriol. 2012 May;194(9):2395.

Composition of pomegranate juice. Krueger DA. J AOAC Int. 2012 Jan-Feb;95(1):163-8.

Ethnobotanical survey and antibacterial activity of plants used in the Altiplane region of Mexico for the treatment of oral cavity infections. Rosas-Piñón Y, Mejía A, Díaz-Ruiz G, Aguilar MI, Sánchez-Nieto S, Rivero-Cruz JF. J Ethnopharmacol. 2012 Mar 23. [Epub ahead of print]

Intestinal Ellagitannin Metabolites Ameliorate Cytokine-Induced Inflammation and Associated Molecular Markers in Human Colon Fibroblasts. Giménez-Bastida JA, Larrosa M, González-Sarrías A, Tomás-Barberán F, Espín JC, García-Conesa MT. J Agric Food Chem. 2012 Apr 16. [Epub ahead of print]

Antioxidant capacities of phenolic compounds and tocopherols from Tunisian pomegranate (Punica granatum) fruits. Elfalleh W, Tlili N, Nasri N, Yahia Y, Hannachi H, Chaira N, Ying M, Ferchichi A. J Food Sci. 2011 Jun-Jul;76(5):C707-13. Epub 2011 Apr 27.

Potential risks resulting from fruit/vegetable-drug interactions: effects on drug-metabolizing enzymes and drug transporters. Rodríguez-Fragoso L, Martínez-Arismendi JL, Orozco-Bustos D, Reyes-Esparza J, Torres E, Burchiel SW. J Food Sci. 2011 May;76(4):R112-24.

Antioxidant capacity changes of 3 cultivar Chinese pomegranate (Punica granatum L.) juices and corresponding wines. Zhuang H, Du J, Wang Y. J Food Sci. 2011 May;76(4):C606-11.

Increased antioxidant content in juice enriched with dried extract of pomegranate (Punica granatum) Peel. Mastrodi Salgado J, Baroni Ferreira TR, de Oliveira Biazotto F, Dos Santos Dias CT. Plant Foods Hum Nutr. 2012 Mar;67(1):39-43.

Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts. Chen B, Tuuli MG, Longtine MS, Shin JS, Lawrence R, Inder T, Michael Nelson D. Am J Physiol Endocrinol Metab. 2012 May;302(9):E1142-52. Epub 2012 Feb 28.

Obesity: The preventive role of the pomegranate (Punica granatum). Al-Muammar MN, Khan F. Nutrition. 2012 Feb 16. [Epub ahead of print]

Comparative study of the anti-inflammatory and antinociceptive effects of two varieties of Punica granatum. Ouachrif A, Khalki H, Chaib S, Mountassir M, Aboufatima R, Farouk L, Benharraf A, Chait A. Pharm Biol. 2012 Apr;50(4):429-38. Epub 2012 Feb 1.

Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs. Zhang XF, Dai YC, Zhong W, Tan M, Lv ZP, Zhou YC, Jiang X. Bioorg Med Chem. 2012 Feb 15;20(4):1616-23. Epub 2011 Nov 30.

Anti-urolithiatic effects of Punica granatum in male rats. Rathod NR, Biswas D, Chitme HR, Ratna S, Muchandi IS, Chandra R. J Ethnopharmacol. 2012 Mar 27;140(2):234-8. Epub 2012 Jan 20.

Effect of Pomegranate Juice on Intestinal Transport and Pharmacokinetics of Nitrendipine in Rats. Voruganti S, Yamsani SK, Ravula SK, Gannu R, Yamsani MR. Phytother Res. 2012 Jan 25. [Epub ahead of print]

Tannase Production by Penicillium purpurogenum PAF6 in Solid State Fermentation of Tannin-Rich Plant Residues Following OVAT and RSM. Jana A, Maity C, Halder SK, Mondal KC, Pati BR, Mohapatra PK. Appl Biochem Biotechnol. 2012 Jan 22. [Epub ahead of print]

Potentiation of dietary restriction-induced lifespan extension by polyphenols. Aires DJ, Rockwell G, Wang T, Frontera J, Wick J, Wang W, Tonkovic-Capin M, Lu J, E L, Zhu H, Swerdlow RH. Biochim Biophys Acta. 2012 Apr;1822(4):522-6. Epub 2012 Jan 11.

Total phenols and antioxidant capacity in 10 Moroccan pomegranate varieties. Legua P, Melgarejo P, Abdelmajid H, Martínez JJ, Martínez R, Ilham H, Hafida H, Hernández F. J Food Sci. 2012 Jan;77(1):C115-20.

55-week treatment of mice with the unani and ayurvedic medicine pomegranate flower ameliorates ageing-associated insulin resistance and skin abnormalities. Wang J, Rong X, Um IS, Yamahara J, Li Y. Evid Based Complement Alternat Med. 2012;2012:350125. Epub 2011 Dec 28.

Assay dilution factors confound measures of total antioxidant capacity in polyphenol-rich juices. Bolling BW, Chen YY, Kamil AG, Oliver Chen CY. J Food Sci. 2012 Feb;77(2):H69-75. Epub 2012 Jan 17.

Pomegranate seed oil in women with menopausal symptoms: a prospective randomized, placebo-controlled, double-blinded trial. Auerbach L, Rakus J, Bauer C, Gerner C, Ullmann R, Wimmer H, Huber J. Menopause. 2012 Apr;19(4):426-32.

Ellagic acid in pomegranate suppresses resistin secretion by a novel regulatory mechanism involving the degradation of intracellular resistin protein in adipocytes. Makino-Wakagi Y, Yoshimura Y, Uzawa Y, Zaima N, Moriyama T, Kawamura Y. Biochem Biophys Res Commun. 2012 Jan 13;417(2):880-5. Epub 2011 Dec 20.

Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model. Adhami VM, Siddiqui IA, Syed DN, Lall RK, Mukhtar H. Carcinogenesis. 2012 Mar;33(3):644-51. Epub 2011 Dec 22.

Pomegranate Fruit Extract Inhibits UVB-induced Inflammation and Proliferation by Modulating NF-κB and MAPK Signaling Pathways in Mouse Skin. Khan N, Syed DN, Pal HC, Mukhtar H, Afaq F. Photochem Photobiol. 2011 Dec 19. [Epub ahead of print]

Pomegranate (Punica granatum L.) flower improves learning and memory performances impaired by diabetes mellitus in rats. Cambay Z, Baydas G, Tuzcu M, Bal R. Acta Physiol Hung. 2011 Dec;98(4):409-20.

Complementary and alternative medicines use by Scottish women with breast cancer. What, why and the potential for drug interactions? McLay JS, Stewart D, George J, Rore C, Heys SD. Eur J Clin Pharmacol. 2012 May;68(5):811-9. Epub 2011 Dec 14.

Determination of lignans in edible and nonedible parts of pomegranate (Punica granatum L.) and products derived therefrom, particularly focusing on the quantitation of isolariciresinol using HPLC-DAD-ESI/MSn. Fischer UA, Jaksch AV, Carle R, Kammerer DR. J Agric Food Chem. 2012 Jan 11;60(1):283-92. Epub 2011 Dec 23.

Pomegranate as a functional food and nutraceutical source. Johanningsmeier SD, Harris GK. Annu Rev Food Sci Technol. 2011;2:181-201. Review.

Molecular genetic diversity of Punica granatum L. (pomegranate) as revealed by microsatellite DNA markers (SSR). Hasnaoui N, Buonamici A, Sebastiani F, Mars M, Zhang D, Vendramin GG. Gene. 2012 Feb 1;493(1):105-12. Epub 2011 Nov 20.

High-capacity calcium-binding chitinase III from pomegranate seeds (Punica granatum Linn.) is located in amyloplasts. Lv C, Masuda T, Yang H, Sun L, Zhao G. Plant Signal Behav. 2011 Dec;6(12):1963-5.

Effect of pomegranate juice on the pharmacokinetics of nitrendipine in rabbits. Voruganti S, Rapolu K, Tota S, Yamsani SK, Yamsani MR. Eur J Drug Metab Pharmacokinet. 2011 Nov 22. [Epub ahead of print]

Bioactive actions of pomegranate fruit extracts on leukemia cell lines in vitro hold promise for new therapeutic agents for leukemia. Dahlawi H, Jordan-Mahy N, Clench MR, Le Maitre CL. Nutr Cancer. 2012;64(1):100-10. Epub 2011 Nov 18.

Acute and long term effects of grape and pomegranate juice consumption on endothelial dysfunction in pediatric metabolic syndrome. Kelishadi R, Gidding SS, Hashemi M, Hashemipour M, Zakerameli A, Poursafa P. J Res Med Sci. 2011 Mar;16(3):245-53.

Polyphenols: skin photoprotection and inhibition of photocarcinogenesis. Afaq F, Katiyar SK. Mini Rev Med Chem. 2011 Dec 1;11(14):1200-15.

Effect of pomegranate seed oil on serum TNF-a level in dyslipidemic patients. Asghari G, Sheikholeslami S, Mirmiran P, Chary A, Hedayati M, Shafiee A, Azizi F. Int J Food Sci Nutr. 2011 Nov 2. [Epub ahead of print]

Pharmacological investigations of Punica granatum in glycerol-induced acute renal failure in rats. Singh AP, Singh AJ, Singh N. Indian J Pharmacol. 2011 Sep;43(5):551-6.

Essential and toxic elements in three Pakistan's medicinal fruits (Punica granatum Ziziphus jujuba and Piper cubeba) analysed by INAA. Fatima I, Waheed S, Zaidi JH. Int J Food Sci Nutr. 2011 Oct 21. [Epub ahead of print]

Evaluation of antioxidant, antitumor and immunomodulatory properties of polysaccharide isolated from fruit rind of Punica granatum. Joseph MM, Aravind SR, Varghese S, Mini S, Sreelekha TT. Mol Med Report. 2011 Oct 18. [Epub ahead of print]

Antibacterial and antifungal activities of punica granatum peel extracts against oral pathogens. Abdollahzadeh Sh, Mashouf R, Mortazavi H, Moghaddam M, Roozbahani N, Vahedi M. J Dent (Tehran). 2011 Winter;8(1):1-6. Epub 2011 Mar 31.

Exploring the Transcriptome Landscape of Pomegranate Fruit Peel for Natural Product Biosynthetic Gene and SSR Marker Discovery. Ono NN, Britton MT, Fass JN, Nicolet CM, Lin D, Tian L. J Integr Plant Biol. 2011 Sep 12.[Epub ahead of print]

Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Balbir-Gurman A, Fuhrman B, Braun-Moscovici Y, Markovits D, Aviram M. Isr Med Assoc J. 2011 Aug;13(8):474-9.

Inhibitory effect of pomegranate on intestinal sodium dependent glucose uptake. Kim HK, Baek SS, Cho HY. Am J Chin Med. 2011;39(5):1015-27.

Pomegranate extract induces cell cycle arrest and alters cellular phenotype of human pancreatic cancer cells. Nair V, Dai Z, Khan M, Ciolino HP. Anticancer Res. 2011 Sep;31 (9):2699-704.

The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates ß-cell insulin release. Koren-Gluzer M, Aviram M, Meilin E, Hayek T. Atherosclerosis. 2011 Aug 4. [Epub ahead of print]

The Antioxidant Potency of Punica granatum L. Fruit Peel Reduces Cell Proliferation and Induces Apoptosis on Breast Cancer. Dikmen M, Ozturk N, Ozturk Y. J Med Food. 2011 Aug 23. [Epub ahead of print]

In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Ishimoto H, Shibata M, Myojin Y, Ito H, Sugimoto Y, Tai A, Hatano T. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5901-4. Epub 2011 Jul 29.

Pomegranate extract demonstrate a selective estrogen receptor modulator profile in human tumor cell lines and in vivo models of estrogen deprivation. Sreeja S, Santhosh Kumar TR, Lakshmi BS, Sreeja S. J Nutr Biochem. 2011 Aug 10. [Epub ahead of print]

Effect of pomegranate juice on insulin secretion and sensitivity in patients with obesity. González-Ortiz M, Martínez-Abundis E, Espinel-Bermúdez MC, Pérez-Rubio KG. Ann Nutr Metab. 2011;58(3):220-3. Epub 2011 Jul 28.

Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation. Rosenblat M, Volkova N, Ward J, Aviram M. Atherosclerosis. 2011 Nov;219(1):49-56. Epub 2011 Jul 12.

The bioactivity of pomegranate: impact on health and disease. Faria A, Calhau C. Crit Rev Food Sci Nutr. 2011 Aug;51(7):626-34.

Chitinase III in pomegranate seeds (Punica granatum Linn.): a high-capacity calcium-binding protein in amyloplasts. Yang H, Zhang T, Masuda T, Lv C, Sun L, Qu G, Zhao G. Plant J. 2011 Jul 26. [Epub ahead of print]

Continuous and pulsed ultrasound-assisted extractions of antioxidants from pomegranate peel. Pan Z, Qu W, Ma H, Atungulu GG, McHugh TH. Ultrason Sonochem. 2012 Mar;19(2):365-72. Epub 2011 May 25.

Effects of pomegranate extracts on cartilage, bone and mesenchymal cells of mouse fetuses. Monsefi M, Parvin F, Talaei-Khozani T. Br J Nutr. 2011 Jul 25:1-8. [Epub ahead of print]

Time-dependent effects of pomegranate juice and pomegranate polyphenols on foodborne viral reduction. Su X, Sangster MY, D'Souza DH. Foodborne Pathog Dis. 2011 Nov;8(11):1177-83. Epub 2011 Jul 21.

Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease. Rosillo MA, Sanchez-Hidalgo M, Cárdeno A, de la Lastra CA. Biochem Pharmacol. 2011 Oct 1;82(7):737-45. Epub 2011 Jul 7.

In vitro antimalarial activity and cytotoxicity of some selected cuban medicinal plants. Valdés AF, Martínez JM, Lizama RS, Gaitén YG, Rodríguez DA, Payrol JA. Rev Inst Med Trop Sao Paulo. 2010 Aug;52(4):197-201.

In vitro antibacterial activity of some Iranian medicinal plant extracts against Helicobacter pylori. Hajimahmoodi M, Shams-Ardakani M, Saniee P, Siavoshi F, Mehrabani M, Hosseinzadeh H, Foroumadi P, Safavi M, Khanavi M, Akbarzadeh T, Shafiee A, Foroumadi A. Nat Prod Res. 2011 Jul;25(11):1059-66.

Antioxidant and antiatherogenic effects of pomegranate. Haber SL, Joy JK, Largent R. Am J Health Syst Pharm. 2011 Jul 15;68(14):1302-5. 

Total phenolic distribution of juice, peel, and seed extracts of four pomegranate cultivars. Gözlekçi S, Saraçoglu O, Onursal E, Ozgen M. Pharmacogn Mag. 2011 Apr;7(26):161-4.

Pomegranate sensitizes Tamoxifen action in ER-a positive breast cancer cells. Banerjee S, Kambhampati S, Haque I, Banerjee SK. J Cell Commun Signal. 2011 Jun 27. [Epub ahead of print]

Delphinidin, a specific inhibitor of histone acetyltransferase, suppresses inflammatory signaling via prevention of NF-?B acetylation in fibroblast-like synoviocyte MH7A cells. Seong AR, Yoo JY, Choi K, Lee MH, Lee YH, Lee J, Jun W, Kim S, Yoon HG. Biochem Biophys Res Commun. 2011 Jul 8;410(3):581-6. Epub 2011 Jun 12.

Dissipation and distribution behavior of azoxystrobin, carbendazim, and difenoconazole in pomegranate fruits. Utture SC, Banerjee K, Dasgupta S, Patil SH, Jadhav MR, Wagh SS, Kolekar SS, Anuse MA, Adsule PG. J Agric Food Chem. 2011 Jul 27;59(14):7866-73. Epub 2011 Jun 21.

The effect of pomegranate juice supplementation on strength and soreness after eccentric exercise. Trombold JR, Reinfeld AS, Casler JR, Coyle EF. J Strength Cond Res. 2011 Jul;25(7):1782-8.

A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development. Ben-Simhon Z, Judeinstein S, Nadler-Hassar T, Trainin T, Bar-Ya'akov I, Borochov-Neori H, Holland D. Planta. 2011 Nov;234(5):865-81. Epub 2011 Jun 5.

Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice. Choi SJ, Lee JH, Heo HJ, Cho HY, Kim HK, Kim CJ, Kim MO, Suh SH, Shin DH. J Med Food. 2011 Jul-Aug;14(7-8):695-701. Epub 2011 Jun 1.

Pomegranate (Punica granatum) Juices: Chemical Composition, Micronutrient Cations, and Antioxidant Capacity. El Kar C, Ferchichi A, Attia F, Bouajila J. J Food Sci. 2011 May 27. [Epub ahead of print]

New microsatellite loci for pomegranate, Punica granatum (Lythraceae). Currò S, Caruso M, Distefano G, Gentile A, La Malfa S. Am J Bot. 2010 Jul;97(7):e58-60. Epub 2010 Jun 16.

Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. Wang L, Alcon A, Yuan H, Ho J, Li QJ, Martins-Green M. Integr Biol (Camb). 2011 Jul;3(7):742-54. Epub 2011 May 19.

Survival of human norovirus surrogates in milk, orange, and pomegranate juice, and juice blends at refrigeration (4 °C). Horm KM, D'Souza DH. Food Microbiol. 2011 Aug;28(5):1054-61. Epub 2011 Mar 2.

Pomegranate seed extract attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity in rats. Cayir K, Karadeniz A, Simsek N, Yildirim S, Karakus E, Kara A, Akkoyun HT, Sengül E. J Med Food. 2011 Oct;14(10):1254-62. Epub 2011 May 6.

Volatile composition of pomegranates from 9 Spanish cultivars using headspace solid phase microextraction. Melgarejo P, Calín-Sánchez Á, Vázquez-Araújo L, Hernández F, Martínez JJ, Legua P, Carbonell-Barrachina ÁA. J Food Sci. 2011 Jan-Feb;76(1):S114-20. Epub 2011 Jan 6.

Mass transfer kinetics during osmotic dehydration of pomegranate arils. Mundada M, Hathan BS, Maske S. J Food Sci. 2011 Jan-Feb;76(1):E31-9. Epub 2010 Dec 1.

Sensory and physicochemical characterization of juices made with pomegranate and blueberries, blackberries, or raspberries. Vázquez-Araújo L, Chambers E 4th, Adhikari K, Carbonell-Barrachina ÁA. J Food Sci. 2010 Sep;75(7):S398-404. 

Optimization of extraction conditions of total phenolics, antioxidant activities, and anthocyanin of oregano, thyme, terebinth, and pomegranate. Rababah TM, Banat F, Rababah A, Ereifej K, Yang W. J Food Sci. 2010 Sep;75(7):C626-32.

Climate effects on anthocyanin accumulation and composition in the pomegranate (Punica granatum L.) fruit arils. Borochov-Neori H, Judeinstein S, Harari M, Bar-Ya'akov I, Patil BS, Lurie S, Holland D. J Agric Food Chem. 2011 May 25;59(10):5325-34. Epub 2011 May 3.

Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam: an open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers. Misaka S, Nakamura R, Uchida S, Takeuchi K, Takahashi N, Inui N, Kosuge K, Yamada S, Watanabe H. Clin Ther. 2011 Feb;33(2):246-52.

Phytochemical characterisation for industrial use of pomegranate (Punica granatum L.) cultivars grown in Spain. Mena P, García-Viguera C, Navarro-Rico J, Moreno DA, Bartual J, Saura D, Martí N. J Sci Food Agric. 2011 Aug 15;91(10):1893-906. Epub 2011 Apr 7.

Hydroalcoholic extract based-ointment from Punica granatum L. peels with enhanced in vivo healing potential on dermal wounds. Hayouni EA, Miled K, Boubaker S, Bellasfar Z, Abedrabba M, Iwaski H, Oku H, Matsui T, Limam F, Hamdi M. Phytomedicine. 2011 Aug 15;18(11):976-84. Epub 2011 Apr 3.

The effects of pomegranate juice consumption on blood pressure and cardiovascular health. Stowe CB.Complement Ther Clin Pract. 2011 May;17(2):113-5. 

Pomegranate seeds in the bone marrow as a clue of hematophagocytosis. Salemme M, Facchetti F. Int J Surg Pathol. 2011 Apr;19(2):193. Epub 2011 Mar 29. 

Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: evidence for inhibition of activated MAPKs/NF-?B and reduced cell proliferation. George J, Singh M, Srivastava AK, Bhui K, Shukla Y. Food Chem Toxicol. 2011 Jul;49(7):1511-20. Epub 2011 Apr 2.

Reduction of cisplatin ototoxicity in rats by oral administration of pomegranate extract. Yazici ZM, Meric A, Midi A, Arinc YV, Kahya V, Hafiz G. Eur Arch Otorhinolaryngol. 2011 Mar 27. [Epub ahead of print]

Pomegranate seed oil, a rich source of punicic acid, prevents diet-induced obesity and insulin resistance in mice. Vroegrijk IO, van Diepen JA, van den Berg S, Westbroek I, Keizer H, Gambelli L, Hontecillas R, Bassaganya-Riera J, Zondag GC, Romijn JA, Havekes LM, Voshol PJ. Food Chem Toxicol. 2011 Jun;49(6):1426-30. Epub 2011 Mar 31.

Genetic relationships among wild pomegranate (Punica granatum) genotypes from Coruh Valley in Turkey. Ercisli S, Gadze J, Agar G, Yildirim N, Hizarci Y. Genet Mol Res. 2011 Mar 15;10(1):459-64.

Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate. Leiva KP, Rubio J, Peralta F, Gonzales GF. Toxicol Mech Methods. 2011 Jul;21(6):495-502. Epub 2011 Mar 21.

Effect of a mixed herb-enriched diet on the innate immune response and disease resistance of Paralichthys olivaceus against Philasterides dicentrarchi infection. Harikrishnan R, Balasundaram C, Kim MC, Kim JS, Han YJ, Heo MS. J Aquat Anim Health. 2010 Dec;22(4):235-43.

Survival of Lactobacillus plantarum in model solutions and fruit juices. Nualkaekul S, Charalampopoulos D. Int J Food Microbiol. 2011 Mar 30;146(2):111-7. Epub 2011 Mar 14.

The pomegranate has many veils. Knauf K. J Pastoral Care Counsel. 2010 Fall;64(3):8.1. 

Effects of mass ratio, pH, temperature, and reaction time on fabrication of partially purified pomegranate ellagitannin-gelatin nanoparticles. Li Z, Gu L. J Agric Food Chem. 2011 Apr 27;59(8):4225-31. Epub 2011 Mar 21.

Cardioprotective effect of whole fruit extract of pomegranate on doxorubicin-induced toxicity in rat. Hassanpour Fard M, Ghule AE, Bodhankar SL, Dikshit M. Pharm Biol. 2011 Apr;49(4):377-82. Epub 2011 Mar 11.

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. Bishayee A, Bhatia D, Thoppil RJ, Darvesh AS, Nevo E, Lansky EP. Carcinogenesis. 2011 Jun;32(6):888-96. Epub 2011 Mar 9.

An aqueous pomegranate peel extract inhibits neutrophil myeloperoxidase in vitro and attenuates lung inflammation in mice. Bachoual R, Talmoudi W, Boussetta T, Braut F, El-Benna J. Food Chem Toxicol. 2011 Jun;49(6):1224-8. Epub 2011 Mar 3.

Fabrication of nanoparticles using partially purified pomegranate ellagitannins and gelatin and their apoptotic effects. Li Z, Percival SS, Bonard S, Gu L. Mol Nutr Food Res. 2011 Jul;55(7):1096-103. Epub 2011 Mar 4.

Antioxidant effect of pomegranate extract in reducing acute inflammation due to myringotomy. Kahya V, Meric A, Yazici M, Yuksel M, Midi A, Gedikli O. J Laryngol Otol. 2011 Apr;125(4):370-5. Epub 2011 Feb 25.

Effect of dipping in pomegranate (Punica granatum) fruit juice phenolic solution on the shelf life of chicken meat under refrigerated storage (4°C). Vaithiyanathan S, Naveena BM, Muthukumar M, Girish PS, Kondaiah N. Meat Sci. 2011 Jul;88(3):409-14. Epub 2011 Feb 2.

Continuous and pulsed ultrasound-assisted extractions of antioxidants from pomegranate peel. Pan Z, Qu W, Ma H, Atungulu GG, McHugh TH. Ultrason Sonochem. 2011 Sep;18(5):1249-57. Epub 2011 Jan 20.

2-Methyl-pyran-4-one-3-O-ß-D-glucopyranoside isolated from leaves of Punica granatum inhibits the TNFa-induced cell adhesion molecules expression by blocking nuclear transcription factor-?B (NF-?B). Balwani S, Nandi D, Jaisankar P, Ghosh B. Biochimie. 2011 May;93(5):921-30. Epub 2011 Feb 17.

Extensive screening for herbal extracts with potent antioxidant properties. Niwano Y, Saito K, Yoshizaki F, Kohno M, Ozawa T. J Clin Biochem Nutr. 2011 Jan;48(1):78-84. Epub 2010 Dec 28.

Effect of probiotication on antioxidant and antibacterial activities of pomegranate juices from sour and sweet cultivars. Fazeli MR, Bahmani S, Jamalifar H, Samadi N. Nat Prod Res. 2011 Feb;25(3):288-97.

Screening of certain medicinal plants from India for their anti-quorum sensing activity. Zahin M, Hasan S, Aqil F, Khan MS, Husain FM, Ahmad I. Indian J Exp Biol. 2010 Dec;48(12):1219-24.

Pomegranate (Punica granatum). El-Garhy MF, Abdel-Aaty HM, Morsy TA. J Egypt Soc Parasitol. 2010 Aug;40(2):551.

Analysis of anthocyanins in commercial fruit juices by using nano-liquid chromatography-electrospray-mass spectrometry and high-performance liquid chromatography with UV-vis detector. Fanali C, Dugo L, D'Orazio G, Lirangi M, Dachà M, Dugo P, Mondello L. J Sep Sci. 2011 Jan;34(2):150-9. 

Volatile composition and sensory quality of Spanish pomegranates (Punica granatum L.). Calín-Sánchez A, Martínez JJ, Vázquez-Araújo L, Burló F, Melgarejo P, Carbonell-Barrachina AA. J Sci Food Agric. 2011 Feb;91(3):586-92. Epub 2010 Nov 22.

Pomegranate juice protects macrophages from triglyceride accumulation: inhibitory effect on DGAT1 activity and on triglyceride biosynthesis. Rosenblat M, Aviram M. Ann Nutr Metab. 2011;58(1):1-9. Epub 2011 Jan 6.

The antiplaque efficacy of pomegranate mouthrinse. Bhadbhade SJ, Acharya AB, Rodrigues SV, Thakur SL. Quintessence Int. 2011 Jan;42(1):29-36.

Pomegranate extract, a prooxidant with antiproliferative and proapoptotic activities preferentially towards carcinoma cells. Weisburg JH, Schuck AG, Silverman MS, Ovits-Levy CG, Solodokin LJ, Zuckerbraun HL, Babich H. Anticancer Agents Med Chem. 2010 Oct 1;10(8):634-44.

Antimicrobial potential of some plant extracts against Candida species. Höfling JF, Anibal PC, Obando-Pereda GA, Peixoto IA, Furletti VF, Foglio MA, Gonçalves RB. Braz J Biol. 2010 Nov;70(4):1065-8.

Tissue culture-mediated biotechnological intervention in pomegranate: a review. Naik SK, Chand PK. Plant Cell Rep. 2011 May;30(5):707-21. Epub 2010 Dec 16.

Fatty acids from Tunisian and Chinese pomegranate (Punica granatum L.) seeds. Elfalleh W, Ying M, Nasri N, Sheng-Hua H, Guasmi F, Ferchichi A. Int J Food Sci Nutr. 2011 May;62(3):200-6. Epub 2010 Dec 1.

Growth Inhibitory, Antiandrogenic, and Pro-apoptotic Effects of Punicic Acid in LNCaP Human Prostate Cancer Cells. Gasmi J, Sanderson JT. J Agric Food Chem. 2010 Nov 10. [Epub ahead of print]

Protective effects of Punica granatum in experimentally-induced gastric ulcers. Alam MS, Alam MA, Ahmad S, Najmi AK, Asif M, Jahangir T.Toxicol Mech Methods. 2010 Nov;20(9):572-8. Epub 2010 Sep 16.

Pomegranate extract inhibits the interleukin-1beta-induced activation of MKK-3, p38alpha-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Rasheed Z, Akhtar N, Haqqi TM. Arthritis Res Ther. 2010 Oct 18;12(5):R195. [Epub ahead of print]

LC-DAD-ESI/MS(n) determination of direct condensation flavanol-anthocyanin adducts in pressure extracted pomegranate (Punica granatum L.) juice. Sentandreu E, Navarro JL, Sendra JM. J Agric Food Chem. 2010 Oct 13;58(19):10560-7.

Influenza virus variation in susceptibility to inactivation by pomegranate polyphenols is determined by envelope glycoproteins. Sundararajan A, Ganapathy R, Huan L, Dunlap JR, Webby RJ, Kotwal GJ, Sangster MY. Antiviral Res. 2010 Oct;88(1):1-9. Epub 2010 Jul 14.

Effect of Punica granatum solvent extracts on immune system and disease resistance in Paralichthys olivaceus against lymphocystis disease virus (LDV). Harikrishnan R, Heo J, Balasundaram C, Kim MC, Kim JS, Han YJ, Heo MS. Fish Shellfish Immunol. 2010 Oct;29(4):668-73. Epub 2010 Jul 31.

Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro. Dai Z, Nair V, Khan M, Ciolino HP. Oncol Rep. 2010 Oct;24(4):1087-91.

Oral Feeding of Pomegranate Fruit Extract Inhibits Early Biomarkers of UVB Radiation-induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis. Afaq F, Khan N, Syed DN, Mukhtar H. Photochem Photobiol. 2010 Sep 23. [Epub ahead of print]

Wound healing activity of Malva sylvestris and Punica granatum in alloxan-induced diabetic rats. Pirbalouti AG, Azizi S, Koohpayeh A, Hamedi B. Acta Pol Pharm. 2010 Sep-Oct;67(5):511-6.

Pomegranate juice (PJ) consumption antioxidative properties on mouse macrophages, but not PJ beneficial effects on macrophage cholesterol and triglyceride metabolism, are mediated via PJ-induced stimulation of macrophage PON2. Rosenblat M, Volkova N, Aviram M. Atherosclerosis. 2010 Sep;212(1):86-92. Epub 2010 May 6.

Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats. Jadeja RN, Thounaojam MC, Patel DK, Devkar RV, Ramachandran AV. Cardiovasc Toxicol. 2010 Sep;10(3):174-80.

Effects of feeding polyphenols from pomegranate extract on health, growth, nutrient digestion, and immunocompetence of calves. Oliveira RA, Narciso CD, Bisinotto RS, Perdomo MC, Ballou MA, Dreher M, Santos JE. J Dairy Sci. 2010 Sep;93(9):4280-91.

Genetic diversity in inter-simple sequence repeat profiles across natural populations of Indian pomegranate (Punica granatum L.). Narzary D, Rana TS, Ranade SA. Plant Biol (Stuttg). 2010 Sep 1;12(5):806-13.

Characterization of a potential nutraceutical ingredient: pomegranate (Punica granatum L.) seed oil unsaponifiable fraction. Caligiani A, Bonzanini F, Palla G, Cirlini M, Bruni R. Plant Foods Hum Nutr. 2010 Sep;65(3):277-83.

Potent antifungal activity of extracts and pure compound isolated from pomegranate peels and synergism with fluconazole against Candida albicans. Endo EH, Cortez DA, Ueda-Nakamura T, Nakamura CV, Dias Filho BP. Res Microbiol. 2010 Sep;161(7):534-40. Epub 2010 Jun 10.

In Vitro Effects of Pomegranate Juice and Pomegranate Polyphenols on Foodborne Viral Surrogates. Su X, Sangster MY, D'Souza DH. Foodborne Pathog Dis. 2010 Aug 31. [Epub ahead of print]

Broad spectrum antimutagenic activity of antioxidant active fraction of Punica granatum L. peel extracts. Zahin M, Aqil F, Ahmad I. Mutat Res. 2010 Aug 11. [Epub ahead of print]

NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts. González-Sarrías A, Larrosa M, Tomás-Barberán FA, Dolara P, Espín JC. Br J Nutr. 2010 Aug;104(4):503-12. Epub 2010 Mar 26.

Effect of pomegranate seed oil on hyperlipidaemic subjects: a double-blind placebo-controlled clinical trial. Mirmiran P, Fazeli MR, Asghari G, Shafiee A, Azizi F. Br J Nutr. 2010 Aug;104(3):402-6. Epub 2010 Mar 25.

Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation. Bae JY, Choi JS, Kang SW, Lee YJ, Park J, Kang YH. Exp Dermatol. 2010 Aug;19(8):e182-90.

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. Larrosa M, González-Sarrías A, Yáñez-Gascón MJ, Selma MV, Azorín-Ortuño M, Toti S, Tomás-Barberán F, Dolara P, Espín JC. J Nutr Biochem. 2010 Aug;21(8):717-25. Epub 2009 Jul 18.

Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria. Dell'agli M, Galli GV, Bulgari M, Basilico N, Romeo S, Bhattacharya D, Taramelli D, Bosisio E. Malar J. 2010 Jul 19;9:208.

Antifungal efficacy of Punica granatum, Acacia nilotica, Cuminum cyminum and Foeniculum vulgare on Candida albicans: an in vitro study. Pai MB, Prashant GM, Murlikrishna KS, Shivakumar KM, Chandu GN. Indian J Dent Res. 2010 Jul-Sep;21(3):334-6.

Antioxidant assay-guided purification and LC determination of ellagic acid in pomegranate peel. Panichayupakarananta P, Issuriya A, Sirikatitham A, Wang W. J Chromatogr Sci. 2010 Jul;48(6):456-9.

NMR assignment and characterization of proton exchange of the ellagitannin granatin B. Steinmetz WE. Magn Reson Chem. 2010 Jul;48(7):565-70.

Dietary antioxidants improve arteriogenic erectile dysfunction. Zhang Q, Radisavljevic ZM, Siroky MB, Azadzoi KM. Int J Androl. 2010 Jun 24. [Epub ahead of print]

The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. Bialonska D, Ramnani P, Kasimsetty SG, Muntha KR, Gibson GR, Ferreira D. Int J Food Microbiol. 2010 Jun 15;140(2-3):175-82. Epub 2010 Apr 2.

Prestorage oxalic acid treatment maintained visual quality, bioactive compounds, and antioxidant potential of pomegranate after long-term storage at 2 degrees C. Sayyari M, Valero D, Babalar M, Kalantari S, Zapata PJ, Serrano M. J Agric Food Chem. 2010 Jun 9;58(11):6804-8.

Medicinal plants as immunosuppressive agents in traditional Iranian medicine. Amirghofran Z. Iran J Immunol. 2010 Jun;7(2):65-73.

Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic Wistar rats. Mohan M, Waghulde H, Kasture S. Phytother Res. 2010 Jun;24 Suppl 2:S196-203. Erratum in: Phytother Res. 2010 Jun;24 Suppl 2:S233-4.

Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys. Bouroshaki MT, Sadeghnia HR, Banihasan M, Yavari S. Ren Fail. 2010 Jun;32(5):612-7.

Isolation and Characterization of Novel Microsatellite Markers in Pomegranate (Punica granatum L.). Pirseyedi SM, Valizadehghan S, Mardi M, Ghaffari MR, Mahmoodi P, Zahravi M, Zeinalabedini M, Nekoui SM. Int J Mol Sci. 2010 May 3;11(5):2010-6.

Color, sugars and organic acids composition in aril juices and peel homogenates prepared from different pomegranate accessions. Dafny-Yalin M, Glazer I, Bar-Ilan I, Kerem Z, Holland D, Amir R. J Agric Food Chem. 2010 Apr 14;58(7):4342-52.

Effects of fruit ellagitannin extracts, ellagic acid, and their colonic metabolite, urolithin A, on Wnt signaling. Sharma M, Li L, Celver J, Killian C, Kovoor A, Seeram NP. J Agric Food Chem. 2010 Apr 14;58(7):3965-9.

Efficacy of Punica granatum extract on in-vitro and in-vivo control of Trichomonas vaginalis. El-Sherbini GM, Ibrahim KM, El Sherbiny ET, Abdel-Hady NM, Morsy TA. J Egypt Soc Parasitol. 2010 Apr;40(1):229-44.

Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: studies in vitro and in diabetic patients. Fuhrman B, Volkova N, Aviram M. Nutrition. 2010 Apr;26(4):359-66. Epub 2009 Sep 17.

Antifungal activity of extracts of some plants used in Brazilian traditional medicine against the pathogenic fungus Paracoccidioides brasiliensis. Johann S, Cisalpino PS, Watanabe GA, Cota BB, de Siqueira EP, Pizzolatti MG, Zani CL, de Resende MA. Pharm Biol. 2010 Apr;48(4):388-96.

Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation. Park HM, Moon E, Kim AJ, Kim MH, Lee S, Lee JB, Park YK, Jung HS, Kim YB, Kim SY. Int J Dermatol. 2010 Mar;49(3):276-82.

Ellagitannin consumption improves strength recovery 2-3 d after eccentric exercise. Trombold JR, Barnes JN, Critchley L, Coyle EF. Med Sci Sports Exerc. 2010 Mar;42(3):493-8.

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice. González-Sarrías A, Giménez-Bastida JA, García-Conesa MT, Gómez-Sánchez MB, García-Talavera NV, Gil-Izquierdo A, Sánchez-Alvarez C, Fontana-Compiano LO, Morga-Egea JP, Pastor-Quirante FA, Martínez-Díaz F, Tomás-Barberán FA, Espín JC. Mol Nutr Food Res. 2010 Mar;54(3):311-22.

Anticandidal activity of pomegranate peel extract aerosol as an applicable sanitizing method. Tayel AA, El-Tras WF. Mycoses. 2010 Mar 1;53(2):117-22. Epub 2009 Jan 24.

The effects of pomegranate seed extract and beta-sitosterol on rat uterine contractions. Promprom W, Kupittayanant P, Indrapichate K, Wray S, Kupittayanant S. Reprod Sci. 2010 Mar;17(3):288-96. Epub 2009 Dec 4.

Colon cancer chemopreventive activities of pomegranate ellagitannins and urolithins. Kasimsetty SG, Bialonska D, Reddy MK, Ma G, Khan SI, Ferreira D. J Agric Food Chem. 2010 Feb 24;58(4):2180-7.

Multiresidue analysis of 50 pesticides in grape, pomegranate, and mango by gas chromatography-ion trap mass spectrometry. Savant RH, Banerjee K, Utture SC, Patil SH, Dasgupta S, Ghaste MS, Adsule PG. J Agric Food Chem. 2010 Feb 10;58(3):1447-54.

Acute and long-term effects of grape and pomegranate juice consumption on vascular reactivity in paediatric metabolic syndrome. Hashemi M, Kelishadi R, Hashemipour M, Zakerameli A, Khavarian N, Ghatrehsamani S, Poursafa P. Cardiol Young. 2010 Feb;20(1):73-7. Epub 2010 Feb 22.

Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis. Koyama S, Cobb LJ, Mehta HH, Seeram NP, Heber D, Pantuck AJ, Cohen P. Growth Horm IGF Res. 2010 Feb;20(1):55-62. Epub 2009 Oct 22.

Punicic acid is an omega-5 fatty acid capable of inhibiting breast cancer proliferation. Grossmann ME, Mizuno NK, Schuster T, Cleary MP. Int J Oncol. 2010 Feb;36(2):421-6.

The effects of polyphenol-containing antioxidants on oxidative stress and lipid peroxidation in Type 2 diabetes mellitus without complications. Fenercioglu AK, Saler T, Genc E, Sabuncu H, Altuntas Y. J Endocrinol Invest. 2010 Feb;33(2):118-24. Epub 2009 Oct 15.

Pomegranate and breast cancer: possible mechanisms of prevention. Sturgeon SR, Ronnenberg AG. Nutr Rev. 2010 Feb;68(2):122-8. Review.

Preparation method and stability of ellagic acid-rich pomegranate fruit peel extract. Panichayupakaranant P, Itsuriya A, Sirikatitham A. Pharm Biol. 2010 Feb;48(2):201-5.

Chondroprotective effects of pomegranate juice on monoiodoacetate-induced osteoarthritis of the knee joint of mice. Hadipour-Jahromy M, Mozaffari-Kermani R. Phytother Res. 2010 Feb;24(2):182-5.

Apoptosis by dietary agents for prevention and treatment of prostate cancer. Khan N, Adhami VM, Mukhtar H. Endocr Relat Cancer. 2010 Jan 29;17(1):R39-52. Print 2010 Mar. Review.

Rooting response of five pomegranate varieties to indole butyric acid concentration and cuttings age. Owais SJ. Pak J Biol Sci. 2010 Jan 15;13(2):51-8.

The wound healing activity of flower extracts of Punica granatum and Achillea kellalensis in Wistar rats. Pirbalouti AG, Koohpayeh A, Karimi I. Acta Pol Pharm. 2010 Jan-Feb;67(1):107-10. No abstract available.

Beyond the antioxidant properties: pomegranate juice polyphenols increase hepatocyte paraoxonase 1 secretion. Gugliucci A. Atherosclerosis. 2010 Jan;208(1):28-9. Epub 2009 Oct 2. No abstract available.

Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway. Khateeb J, Gantman A, Kreitenberg AJ, Aviram M, Fuhrman B. Atherosclerosis. 2010 Jan;208(1):119-25. Epub 2009 Sep 6.

Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Adams LS, Zhang Y, Seeram NP, Heber D, Chen S. Cancer Prev Res (Phila). 2010 Jan;3(1):108-13.

Possible interaction between pomegranate juice and warfarin. Jarvis S, Li C, Bogle RG. Emerg Med J. 2010 Jan;27(1):74-5.

Pomegranate (Punica granatum) seed linolenic acid isomers: concentration-dependent modulation of estrogen receptor activity. Tran HN, Bae SY, Song BH, Lee BH, Bae YS, Kim YH, Lansky EP, Newman RA. Endocr Res. 2010 Jan;35(1):1-16.

Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir. Haidari M, Ali M, Ward Casscells S 3rd, Madjid M. Phytomedicine. 2009 Dec;16(12):1127-36. Epub 2009 Jul 7.

The Effects of Pomegranate Seed Extract and B-Sitosterol on Rat Uterine Contractions. Promprom W, Kupittayanant P, Indrapichate K, Wray S, Kupittayanant S. Reprod Sci. 2009 Dec 4.

Ellagitannin Consumption Improves Strength Recovery 2-3 Days after Eccentric Exercise. Trombold JR, Barnes JN, Critchley L, Coyle EF. Med Sci Sports Exerc. 2009 Nov 23.

Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. Kasimsetty SG, Bialonska D, Reddy MK, Thornton C, Willett KL, Ferreira D. J Agric Food Chem. 2009 Nov 25;57(22):10636-44.

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice. González-Sarrías A, Giménez-Bastida JA, García-Conesa MT, Gómez-Sánchez MB, García-Talavera NV, Gil-Izquierdo A, Sánchez-Álvarez C, Fontana-Compiano LO, Morga-Egea JP, Pastor-Quirante FA, Martínez-Díaz F, Tomás-Barberán FA, Espín JC. Mol Nutr Food Res. 2009 Nov 2.

Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis. Koyama S, Cobb LJ, Mehta HH, Seeram NP, Heber D, Pantuck AJ, Cohen P. Growth Horm IGF Res. 2009 Oct 21.

Beyond the antioxidant properties: Pomegranate juice polyphenols increase hepatocyte paraoxonase 1 secretion. Gugliucci A. Atherosclerosis. 2009 Oct 2.

Effects of pomegranate juice on hyperoxaluria-induced oxidative stress in the rat kidneys. Ilbey YO, Ozbek E, Simsek A, Cekmen M, Somay A, Tasci AI. Ren Fail. 2009;31(6):522-31.

Antimicrobial pomegranate rind extracts: enhancement by Cu(II) and vitamin C combinations against clinical isolates of Pseudomonas aeruginosa. Gould SW, Fielder MD, Kelly AF, El Sankary W, Naughton DP. Br J Biomed Sci. 2009;66(3):129-32.

Urolithins, intestinal microbial metabolites of pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay. Bialonska D, Kasimsetty SG, Khan SI, Ferreira D. J Agric Food Chem. 2009 Nov 11;57(21):10181-6.

Pomegranate fruit extract impairs invasion and motility in human breast cancer. Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD. Integr Cancer Ther. 2009 Sep;8(3):242-53.

Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: A role for PPAR-gamma pathway. Khateeb J, Gantman A, Kreitenberg AJ, Aviram M, Fuhrman B. Atherosclerosis. 2009 Sep 6.

Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease. Davidson MH, Maki KC, Dicklin MR, Feinstein SB, Witchger M, Bell M, McGuire DK, Provost JC, Liker H, Aviram M. Am J Cardiol. 2009 Oct 1;104(7):936-42.

Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: Studies in vitro and in diabetic patients. Fuhrman B, Volkova N, Aviram M. Nutrition. 2009 Sep 15.

Antioxidant Capacity and Lipid Characterization of Six Georgia-Grown Pomegranate Cultivars. Pande G, Akoh CC. J Agric Food Chem. 2009 Sep 10.

Pomegranate (Punica granatum) allergy: clinical and immunological findings. Damiani E, Aloia AM, Priore MG, Nardulli S, Ferrannini A. Ann Allergy Asthma Immunol. 2009 Aug;103(2):178-80.

Environmental conditions affect the color, taste, and antioxidant capacity of 11 pomegranate accessions' fruits. Schwartz E, Tzulker R, Glazer I, Bar-Ya'akov I, Wiesman Z, Tripler E, Bar-Ilan I, Fromm H, Borochov-Neori H, Holland D, Amir R. J Agric Food Chem. 2009 Oct 14;57(19):9197-209.

Toxicological evaluation of pomegranate seed oil. Meerts IA, Verspeek-Rip CM, Buskens CA, Keizer HG, Bassaganya-Riera J, Jouni ZE, van Huygevoort AH, van Otterdijk FM, van de Waart EJ. Food Chem Toxicol. 2009 Feb 2.

The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria. Bialonska D, Kasimsetty SG, Schrader KK, Ferreira D. J Agric Food Chem. 2009 Sep 23;57(18):8344-9.

In vitro and In vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract Against Salmonella. Choi JG, Kang OH, Lee YS, Chae HS, Oh YC, Brice OO, Kim MS, Sohn DH, Kim HS, Park H, Shin DW, Rho JR, Kwon DY. Evid Based Complement Alternat Med. 2009 Aug 17.

Physico-chemical properties and DPPH-ABTS scavenging activity of some local pomegranate (Punica granatum) ecotypes. Elfalleh W, Nasri N, Marzougui N, Thabti I, M'rabet A, Yahya Y, Lachiheb B, Guasmi F, Ferchichi A. Int J Food Sci Nutr. 2009;60 Suppl 2:197-210.

Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. Boussetta T, Raad H, Lettéron P, Gougerot-Pocidalo MA, Marie JC, Driss F, El-Benna J. PLoS One. 2009 Jul 31;4(7):e6458.

Potential interaction between pomegranate juice and warfarin. Komperda KE. Pharmacotherapy. 2009 Aug;29(8):1002-6.

Anti-microbial activities of pomegranate rind extracts: enhancement by cupric sulphate against clinical isolates of S. aureus, MRSA and PVL positive CA-MSSA. Gould SW, Fielder MD, Kelly AF, Naughton DP. BMC Complement Altern Med. 2009 Jul 27;9:23.

Antimicrobial activity of pomegranate (Punica granatum L.) fruit peels. Al-Zoreky NS. Int J Food Microbiol. 2009 Sep 15;134(3):244-8.

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. Larrosa M, González-Sarrías A, Yáñez-Gascón MJ, Selma MV, Azorín-Ortuño M, Toti S, Tomás-Barberán F, Dolara P, Espín JC. J Nutr Biochem. 2009 Jul 17.

Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir. Haidari M, Ali M, Ward Casscells S 3rd, Madjid M. Phytomedicine. 2009 Dec;16(12):1127-36.

Antiplasmodial activity of Punica granatum L. fruit rind. Dell'Agli M, Galli GV, Corbett Y, Taramelli D, Lucantoni L, Habluetzel A, Maschi O, Caruso D, Giavarini F, Romeo S, Bhattacharya D, Bosisio E. J Ethnopharmacol. 2009 Sep 7;125(2):279-85.

The role of pomegranate (Punica granatum L.) in colon cancer. Khan SA. Pak J Pharm Sci. 2009 Jul;22(3):346-8.

Chondroprotective effects of pomegranate juice on monoiodoacetate-induced osteoarthritis of the knee joint of mice. Hadipour-Jahromy M, Mozaffari-Kermani R. Phytother Res. 2009 Jun 5.

Punica granatum peel extract protects against ionizing radiation-induced enteritis and leukocyte apoptosis in rats. Toklu HZ, Sehirli O, Ozyurt H, Mayada?li AA, Ek?io?lu-Demiralp E, Cetinel S, Sahin H, Ye?en BC, Ulusoylu Dumlu M, Gökmen V, Sener G. J Radiat Res (Tokyo). 2009 Jul;50(4):345-53.

Antimicrobial activity of six pomegranate (Punica granatum L.) varieties and their relation to some of their pomological and phytonutrient characteristics. Duman AD, Ozgen M, Dayisoylu KS, Erbil N, Durgac C. Molecules. 2009 May 13;14(5):1808-17.

Effects of pomegranate juice and extract polyphenols on platelet function. Mattiello T, Trifirò E, Jotti GS, Pulcinelli FM. J Med Food. 2009 Apr;12(2):334-9.

Pomegranate flower ameliorates fatty liver in an animal model of type 2 diabetes and obesity. Xu KZ, Zhu C, Kim MS, Yamahara J, Li Y. J Ethnopharmacol. 2009 Jun 22;123(2):280-7.

Toxicological evaluation of pomegranate seed oil. Meerts IA, Verspeek-Rip CM, Buskens CA, Keizer HG, Bassaganya-Riera J, Jouni ZE, van Huygevoort AH, van Otterdijk FM, van de Waart EJ. Food Chem Toxicol. 2009 Jun;47(6):1085-92.

Pomegranate: its role in cardiovascular health. Ross SM. Holist Nurs Pract. 2009 May-Jun;23(3):195-7.

Embryo protective effect of pomegranate (Punica granatum L.) fruit extract in adriamycin-induced oxidative stress. Kishore RK, Sudhakar D, Parthasarathy PR. Indian J Biochem Biophys. 2009 Feb;46(1):106-11.

Exploring the ameliorative potential of Punica granatum in dextran sulfate sodium induced ulcerative colitis in mice. Singh K, Jaggi AS, Singh N. Phytother Res. 2009 Nov;23(11):1565-74.

Pomegranate fruit components modulate human thrombin. Cuccioloni M, Mozzicafreddo M, Sparapani L, Spina M, Eleuteri AM, Fioretti E, Angeletti M. Fitoterapia. 2009 Jul;80(5):301-5.

Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. Afaq F, Zaid MA, Khan N, Dreher M, Mukhtar H. Exp Dermatol. 2009 Jun;18(6):553-61.

Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice. Kumar S, Maheshwari KK, Singh V. Indian J Exp Biol. 2008 Dec;46(12):811-6.

Pomegranate extract mouth rinsing effects on saliva measures relevant to gingivitis risk. DiSilvestro RA, DiSilvestro DJ, DiSilvestro DJ. Phytother Res. 2009 Aug;23(8):1123-7.

Pomegranate juice: a heart-healthy fruit juice. Basu A, Penugonda K. Nutr Rev. 2009 Jan;67(1):49-56.

Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Kim YH, Choi EM. Phytother Res. 2009 May;23(5):737-9.

Transport behavior of ellagic acid of pomegranate leaf tannins and its correlation with total cholesterol alteration in HepG2 cells. Lan J, Lei F, Hua L, Wang Y, Xing D, Du L. Biomed Chromatogr. 2009 May;23(5):531-6.

Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects. Guo C, Wei J, Yang J, Xu J, Pang W, Jiang Y. Nutr Res. 2008 Feb;28(2):72-7.

Pomegranate seed oil consumption during a period of high-fat feeding reduces weight gain and reduces type 2 diabetes risk in CD-1 mice. McFarlin BK, Strohacker KA, Kueht ML. Br J Nutr. 2009 Jul;102(1):54-9.

Antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin C. McCarrell EM, Gould SW, Fielder MD, Kelly AF, El Sankary W, Naughton DP. BMC Complement Altern Med. 2008 Dec 15;8:64.

Pomegranate juice inhibits sulfoconjugation in Caco-2 human colon carcinoma cells. Saruwatari A, Okamura S, Nakajima Y, Narukawa Y, Takeda T, Tamura H. J Med Food. 2008 Dec;11(4):623-8.

Comment on safety and antioxidant activity of a pomegranate ellagitannin-enriched polyphenol dietary supplement in overweight individuals with increased waist size. Faria A, Monteiro R, Azevedo I, Calhau C. J Agric Food Chem. 2008 Dec 24;56(24):12143-4.

Protective effect of a potent antioxidant, pomegranate juice, in the kidney of rats with nephrolithiasis induced by ethylene glycol. Tugcu V, Kemahli E, Ozbek E, Arinci YV, Uhri M, Erturkuner P, Metin G, Seckin I, Karaca C, Ipekoglu N, Altug T, Cekmen MB, Tasci AI. J Endourol. 2008 Dec;22(12):2723-31.

Hepatoprotective role and antioxidant capacity of pomegranate (Punica granatum) flowers infusion against trichloroacetic acid-exposed in rats. Celik I, Temur A, Isik I. Food Chem Toxicol. 2009 Jan;47(1):145-9.

Medicinal flowers. XXIII. New taraxastane-type triterpene, punicanolic acid, with tumor necrosis factor-alpha inhibitory activity from the flowers of Punica granatum. Xie Y, Morikawa T, Ninomiya K, Imura K, Muraoka O, Yuan D, Yoshikawa M. Chem Pharm Bull (Tokyo). 2008 Nov;56(11):1628-31.

Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Bagri P, Ali M, Aeri V, Bhowmik M, Sultana S. Food Chem Toxicol. 2009 Jan;47(1):50-4.

Antioxidant properties of peel and pulp hydro extract in ten Persian pomegranate cultivars. Hajimahmoodi M, Oveisi MR, Sadeghi N, Jannat B, Hadjibabaie M, Farahani E, Akrami MR, Namdar R. Pak J Biol Sci. 2008 Jun 15;11(12):1600-4.

Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice. Parmar HS, Kar A. Biofactors. 2007;31(1):17-24.

Pomegranate extract inhibits androgen-independent prostate cancer growth through a nuclear factor-kappaB-dependent mechanism. Rettig MB, Heber D, An J, Seeram NP, Rao JY, Liu H, Klatte T, Belldegrun A, Moro A, Henning SM, Mo D, Aronson WJ, Pantuck A. Mol Cancer Ther. 2008 Sep;7(9):2662-71. Erratum in: Mol Cancer Ther. 2008 Nov;7(11):3654.

Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities. Rock W, Rosenblat M, Miller-Lotan R, Levy AP, Elias M, Aviram M. J Agric Food Chem. 2008 Sep 24;56(18):8704-13.

Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts. Pacheco-Palencia LA, Noratto G, Hingorani L, Talcott ST, Mertens-Talcott SU. J Agric Food Chem. 2008 Sep 24;56(18):8434-41.

Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects. Seeram NP, Zhang Y, McKeever R, Henning SM, Lee RP, Suchard MA, Li Z, Chen S, Thames G, Zerlin A, Nguyen M, Wang D, Dreher M, Heber D. J Med Food. 2008 Jun;11(2):390-4.

Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and thyroid hormones. Parmar HS, Kar A. J Med Food. 2008 Jun;11(2):376-81.

Therapeutic applications of pomegranate (Punica granatum L.): a review. Jurenka JS. Altern Med Rev. 2008 Jun;13(2):128-44.

Safety assessment of pomegranate fruit extract: acute and subchronic toxicity studies. Patel C, Dadhaniya P, Hingorani L, Soni MG. Food Chem Toxicol. 2008 Aug;46(8):2728-35.

Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. J Inflamm (Lond). 2008 Jun 13;5:9.

Traditional medicinal plants of cold desert Ladakh-used against kidney and urinary disorders. Ballabh B, Chaurasia OP, Ahmed Z, Singh SB. J Ethnopharmacol. 2008 Jul 23;118(2):331-9.

Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Nutrition. 2008 Jul-Aug;24(7-8):733-43.

Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor. Hong MY, Seeram NP, Heber D. J Nutr Biochem. 2008 Dec;19(12):848-55.

Multitargeted therapy of cancer by ellagitannins. Heber D. Cancer Lett. 2008 Oct 8;269(2):262-8.

Immune-suppressive activity of punicalagin via inhibition of NFAT activation. Lee SI, Kim BS, Kim KS, Lee S, Shin KS, Lim JS. Biochem Biophys Res Commun. 2008 Jul 11;371(4):799-803.

Ellagic acid, pomegranate and prostate cancer -- a mini review. Bell C, Hawthorne S. J Pharm Pharmacol. 2008 Feb;60(2):139-44.

Analysis of ellagic acid in pomegranate rinds by capillary electrophoresis and high-performance liquid chromatography. Zhou B, Wu Z, Li X, Zhang J, Hu X. Phytochem Anal. 2008 Jan-Feb;19(1):86-9.

Effects of pomegranate juice consumption on sperm quality, spermatogenic cell density, antioxidant activity and testosterone level in male rats. Türk G, Sönmez M, Aydin M, Yüce A, Gür S, Yüksel M, Aksu EH, Aksoy H. Clin Nutr. 2008 Apr;27(2):289-96.

Comparison of antioxidant potency of commonly consumed polyphenol-rich beverages in the United States. Seeram NP, Aviram M, Zhang Y, Henning SM, Feng L, Dreher M, Heber D. J Agric Food Chem. 2008 Feb 27;56(4):1415-22.

Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease. Seeram NP. J Agric Food Chem. 2008 Feb 13;56(3):627-9.

Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo. Sartippour MR, Seeram NP, Rao JY, Moro A, Harris DM, Henning SM, Firouzi A, Rettig MB, Aronson WJ, Pantuck AJ, Heber D. Int J Oncol. 2008 Feb;32(2):475-80.

Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins. Aviram M, Volkova N, Coleman R, Dreher M, Reddy MK, Ferreira D, Rosenblat M. J Agric Food Chem. 2008 Feb 13;56(3):1148-57.

Pomegranate juice effects on cytochrome P450S expression: in vivo studies. Faria A, Monteiro R, Azevedo I, Calhau C. J Med Food. 2007 Dec;10(4):643-9.

Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha/-gamma activator properties. Li Y, Qi Y, Huang TH, Yamahara J, Roufogalis BD. Diabetes Obes Metab. 2008 Jan;10(1):10-7.

Can pomegranate prevent prostate cancer? Pereira M. J Cancer Res Ther. 2007 Jul-Sep;3(3):166.

Isolation and identification of two lipid transfer proteins in pomegranate (Punica granatum). Zoccatelli G, Dalla Pellegrina C, Consolini M, Fusi M, Sforza S, Aquino G, Dossena A, Chignola R, Peruffo A, Olivieri M, Rizzi C. J Agric Food Chem. 2007 Dec 26;55(26):11057-62.

Assessment of the genotoxic risk of Punica granatum L. (Punicaceae) whole fruit extracts. Sánchez-Lamar A, Fonseca G, Fuentes JL, Cozzi R, Cundari E, Fiore M, Ricordy R, Perticone P, Degrassi F, De Salvia R. J Ethnopharmacol. 2008 Feb 12;115(3):416-22.

Antibacterial activity directed isolation of compounds from Punica granatum. Naz S, Siddiqi R, Ahmad S, Rasool SA, Sayeed SA. J Food Sci. 2007 Nov;72(9):M341-5.

Pomegranate oil analysis with emphasis on MALDI-TOF/MS triacylglycerol fingerprinting. Kaufman M, Wiesman Z. J Agric Food Chem. 2007 Dec 12;55(25):10405-13.

Safety and antioxidant activity of a pomegranate ellagitannin-enriched polyphenol dietary supplement in overweight individuals with increased waist size. Heber D, Seeram NP, Wyatt H, Henning SM, Zhang Y, Ogden LG, Dreher M, Hill JO. J Agric Food Chem. 2007 Nov 28;55(24):10050-4.

Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats. Toklu HZ, Dumlu MU, Sehirli O, Ercan F, Gedik N, Gökmen V, Sener G. J Pharm Pharmacol. 2007 Sep;59(9):1287-95.

Antioxidant activity, polyphenol content, and related compounds in different fruit juices and homogenates prepared from 29 different pomegranate accessions. Tzulker R, Glazer I, Bar-Ilan I, Holland D, Aviram M, Amir R. J Agric Food Chem. 2007 Nov 14;55(23):9559-70.

Anti-oxidants from green tea and pomegranate for chemoprevention of prostate cancer. Adhami VM, Mukhtar H. Mol Biotechnol. 2007 Sep;37(1):52-7.

Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury. West T, Atzeva M, Holtzman DM. Dev Neurosci. 2007;29(4-5):363-72.

Pomegranate ellagitannin-derived metabolites inhibit prostate cancer growth and localize to the mouse prostate gland. Seeram NP, Aronson WJ, Zhang Y, Henning SM, Moro A, Lee RP, Sartippour M, Harris DM, Rettig M, Suchard MA, Pantuck AJ, Belldegrun A, Heber D. J Agric Food Chem. 2007 Sep 19;55(19):7732-7.

Preparative separation of punicalagin from pomegranate husk by high-speed countercurrent chromatography. Lu J, Wei Y, Yuan Q. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 15;857(1):175-9.

Pomegranate wine has greater protection capacity than red wine on low-density lipoprotein oxidation. Sezer ED, Akçay YD, Ilanbey B, Yildirim HK, Sözmen EY. J Med Food. 2007 Jun;10(2):371-4.

Punica granatum: heuristic treatment for diabetes mellitus. Katz SR, Newman RA, Lansky EP. J Med Food. 2007 Jun;10(2):213-7.

Pomegranate derived products for cancer chemoprevention. Syed DN, Afaq F, Mukhtar H. Semin Cancer Biol. 2007 Oct;17(5):377-85. E

Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study. Forest CP, Padma-Nathan H, Liker HR. Int J Impot Res. 2007 Nov-Dec;19(6):564-7.

Antioxidant, antimalarial and antimicrobial activities of tannin-rich fractions, ellagitannins and phenolic acids from Punica granatum L. Reddy MK, Gupta SK, Jacob MR, Khan SI, Ferreira D. Planta Med. 2007 May;73(5):461-7.

The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats. de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Fiorito C, Ignarro LJ, Napoli C. Nitric Oxide. 2007 Aug;17(1):50-4.

Effect of pomegranate (Punica granatum) juice intake on hepatic oxidative stress. Faria A, Monteiro R, Mateus N, Azevedo I, Calhau C. Eur J Nutr. 2007 Aug;46(5):271-8.

Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Khan N, Afaq F, Kweon MH, Kim K, Mukhtar H. Cancer Res. 2007 Apr 1;67(7):3475-82.

Evaluation of antioxidant activity and preventing DNA damage effect of pomegranate extracts by chemiluminescence method. Guo S, Deng Q, Xiao J, Xie B, Sun Z. J Agric Food Chem. 2007 Apr 18;55(8):3134-40.

Cytoprotective effect of preparations from various parts of Punica granatum L. fruits in oxidatively injured mammalian cells in comparison with their antioxidant capacity in cell free systems. Sestili P, Martinelli C, Ricci D, Fraternale D, Bucchini A, Giamperi L, Curcio R, Piccoli G, Stocchi V. Pharmacol Res. 2007 Jul;56(1):18-26.

Antiliperoxidant activity of pomegranate peel extracts on lard. Zhang Q, Jia D, Yao K. Nat Prod Res. 2007 Mar;21(3):211-6.

Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice. Farkas D, Oleson LE, Zhao Y, Harmatz JS, Zinny MA, Court MH, Greenblatt DJ. J Clin Pharmacol. 2007 Mar;47(3):286-94.

Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice. Lei F, Zhang XN, Wang W, Xing DM, Xie WD, Su H, Du LJ. Int J Obes (Lond). 2007 Jun;31(6):1023-9.

Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation. Shiner M, Fuhrman B, Aviram M. Atherosclerosis. 2007 Dec;195(2):313-21.

The application of polyamines by pressure or immersion as a tool to maintain functional properties in stored pomegranate arils. Mirdehghan SH, Rahemi M, Serrano M, Guillén F, Martínez-Romero D, Valero D. J Agric Food Chem. 2007 Feb 7;55(3):755-60.

In vitro studies on the binding, antioxidant, and cytotoxic actions of punicalagin. Kulkarni AP, Mahal HS, Kapoor S, Aradhya SM. J Agric Food Chem. 2007 Feb 21;55(4):1491-500.

Effects of oral administration of ellagic acid-rich pomegranate extract on ultraviolet-induced pigmentation in the human skin. Kasai K, Yoshimura M, Koga T, Arii M, Kawasaki S. J Nutr Sci Vitaminol (Tokyo). 2006 Oct;52(5):383-8.

Punica granatum (pomegranate) extract is active against dental plaque. Menezes SM, Cordeiro LN, Viana GS. J Herb Pharmacother. 2006;6(2):79-92.

A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract. Jimenez Del Rio M, Ramazanov A, Sikorski S, Ramazanov Z, Chkhikvishvili I. Georgian Med News. 2006 Nov;(140):70-7.

Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. Lansky EP, Newman RA. J Ethnopharmacol. 2007 Jan 19;109(2):177-206.

Free radical scavenging, anti-glycation and tyrosinase inhibition properties of a polysaccharide fraction isolated from the rind from Punica granatum. Rout S, Banerjee R. Bioresour Technol. 2007 Nov;98(16):3159-63.

Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. Nagata M, Hidaka M, Sekiya H, Kawano Y, Yamasaki K, Okumura M, Arimori K. Drug Metab Dispos. 2007 Feb;35(2):302-5.

Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers. Mertens-Talcott SU, Jilma-Stohlawetz P, Rios J, Hingorani L, Derendorf H. J Agric Food Chem. 2006 Nov 15;54(23):8956-61.

Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia. Esmaillzadeh A, Tahbaz F, Gaieni I, Alavi-Majd H, Azadbakht L. Int J Vitam Nutr Res. 2006 May;76(3):147-51.

Polyphenols from green tea and pomegranate for prevention of prostate cancer. Adhami VM, Mukhtar H. Free Radic Res. 2006 Oct;40(10):1095-104.

Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis. de Nigris F, Williams-Ignarro S, Sica V, Lerman LO, D'Armiento FP, Byrns RE, Casamassimi A, Carpentiero D, Schiano C, Sumi D, Fiorito C, Ignarro LJ, Napoli C. Cardiovasc Res. 2007 Jan 15;73(2):414-23.

Photochemopreventive effect of pomegranate fruit extract on UVA-mediated activation of cellular pathways in normal human epidermal keratinocytes. Syed DN, Malik A, Hadi N, Sarfaraz S, Afaq F, Mukhtar H. Photochem Photobiol 2006 Mar-Apr;82(2):398-405.

Beware of pomegranates bearing 40% ellagic Acid. Lansky EP. J Med Food 2006 Spring;9(1):119-22.

Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Aslam MN, Lansky EP, Varani J. J Ethnopharmacol 2006 Feb;103(3):311-8.

Dietary effect of pomegranate seed oil on immune function and lipid metabolism in mice. Yamasaki M, Kitagawa T, Koyanagi N, Chujo H, Maeda H, Kohno-Murase J, Imamura J, Tachibana H, Yamada K. Nutrition 2006 Jan;22(1):54-9.

Effects of pomegranate juice consumption on myocardial perfusion in patients with coronary heart disease. Sumner MD, Elliott-Eller M, Weidner G, Daubenmier JJ, Chew MH, Marlin R, Raisin CJ, Ornish D. Amer J Cardio 2005;96:810-814.

Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. Rosenblat M, Hayek T, Aviram M. Atherosclerosis 2005 Oct.

Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages. Fuhrman B, Volkova N, Avram M. J Nut Biochem 2005 Sep;16(9):570-6.

Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic ischemic brain injury. Loren DJ, Seeram NP, Schulman RN, Holtzman DM. Pediatr Res 2005 Mar;17.

Oxidative Stress in Arteriogenic Erectile Dysfunction: Prophylactic Role of Antioxidants. Azadzoi KM, Schulman RN, Aviram M, Siroky MB. J Urology 2005; 174(1):386-393.

Beneficial Effects of Pomegranate Juice on Oxidation-Sensitive Genes and eNos Activity at Sites of Perturbed Shear-Stress. de Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G, D'Armiento FP, De Rosa G, Sica V, Ignarro LJ, Napoli C. Proceedings of the National Academy of Sciences 2005 102(13):4896-4901.

Anthocyanin and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice. Afaq F, Saleem M, Krueger CG, Reed JD, and Mukhtar H. Int J Cancer 2005;113(3):423-33.

Possible synergistic prostate cancer suppression by anatomically discrete pomegranate fractions. Lansky EP, Jiang W, Mo H, Bravo L, Froom P, Yu W, Harris NM, Neeman I, Campbell MJ. Invest New Drugs 2005 Jan;23(1):11-20.

Pomegranate extract inhibits Staphylococcus aureus growth and subsequent enterotoxin production. Braga LC, Shupp JW, Cummings C, Jett M, Takahashi JA, Carmo LS, Chartone-Souza E, Nascimento AM. J Ethnopharmacol 2005 Jan;4;96(1-2):335-9.

Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia. Esmaillzadeh A, Tahbaz F, Gaieni I, Alavi-Majd H, Azadbakht L. J Med Food. 2004 Fall;7(3):305-8.

Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells. Albrecht M, Jiang W, Kumi-Diaka J, Lansky EP,Gommersall LM, Patel A, Mansel RE, Neeman I,Geldof AA, Campbell MJ. J Med Food 2004 Fall;7(3):274-83.

Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide. Neurath AR, Strick N, Li YY, Debnath AK. BMC Infect Dis 2004 Oct;4(1):41.

Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. Seeram NP, Lee R, Heber D. Clinica Chimica Acta 2004 Oct;348(1-2):63-8.

Antioxidant activity of selected foodstuffs. Kelawala NS, Ananthanarayan L. Int J Food Sci Nutr 2004 Sep;55(6):511-6. 

Antiviral activities of medicinal herbs traditionally used in southern mainland China. Li Y, Ooi LS,Wang H, But PP, Ooi VE. Phytother Res 2004 Sep;18(9):718-22.

Breast cancer chemopreventive properties of pomegranate (Punica granatum) fruit extracts in a mouse mammary organ culture. Mehta R, Lansky EP. Eur J Cancer Prev 2004 Aug;13(4):345-8.

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Aviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N, Presser D, Attias J, Liker H, Hayek T. Clin Nutr 2004 Jun;23(3):423-33.

Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice. Mori-Okamoto J, Otawara-Hamamoto Y, Yamato H, Yoshimura H. J Ethnopharmacol 2004 May;92(1):93-101.

Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells. Kawaii S, Lansky EP. J Med Food 2004 Spring;7(1):13-8.

Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry. van Elswijk DA, Schobel UP, Lansky EP, Irth H, van der Greef J. Phytochemistry 2004 Jan;65(2):233-41.

Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats. H Kohno,R Suzuki, Y Yasui, M Hosokawa, K Miyashita, and T Tanaka. Cancer Sci 2004;95(6):481-6.

Repeated oral administration of high doses of pomegranate ellagitannin punicalagin to rats for 37 days is not toxic. Cerda B, Ceron JJ, Tomas-Barberan FA, Espin JC. J Agric Food Chem 2003;51:3493– 501.

Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts. A preliminary study. Sastravaha G, Yotnuengnit P,Booncong P, Sangtherapitikul P. J Int Acad Periodontol 2003 Oct;5(4):106-15.

Use of Punica granatum as an antifungal agent against candidosis associated with denture stomatitis. Vasconcelos LC, Sampaio MC, Sampaio FC, Higino JS. Mycoses 2003 Jun;46 (5-6):192-6.

Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice. Cerda B, Llorach R, Ceron JJ, Espin JC, Tomas-Barberan FA. Eur J Nutr 2003;42:18– 28.

A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants. Schubert SY, Neeman I, Resnick N. FASEB J 2002 Dec;16(14):1931-3.

Chemopreventive effects of pomegranate seed oil on skin tumor development in CD1 mice. Hora JJ, Maydew ER, Lansky EP, Dwivedi C. J Med Food 2003 Fall;6(3):157-61.

Preliminary studies on the anti-angiogenic potential of pomegranate fractions in vitro and in vivo. Toi M, Bando H, Ramachandran C, Melnick SJ, Imai A, Fife RS, Carr RE, Oikawa T, Lansky EP. Angiogenesis 2003;6(2):121-8.

Pharmacokinetic study of ellagic acid in rat after oral administration of pomegranate leaf extract. Lei F, Xing D-M, Xiang L, Zhao Y-N, et al. J Chromatogr B 2003;796:189– 94.

Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans. Aviram M, Dornfeld L,Kaplan M,Coleman R, Gaitini D, Nitecki S, Hofman A, Rosenblat M, Volkova N, Presser D, Attias J, Hayek T, Fuhrman B. Drugs Exp Clin Res 2002;28 (2-3):49-62.

Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. Chidambara Murthy KN, Jayaprakasha GK, Singh RP. J Agric Food Chem. 2002 Aug;50(17):4791-5.

Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Kim ND, Mehta R, Yu W, Neeman I, Livney T, Amichay A, Poirier D, Nicholls P, Kirby A, Jiang W, Mansel R, Ramachandran C, Rabi T, Kaplan B, Lansky E. Breast Cancer Res Treat 2002 Feb;71(3):203-17.

Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Aviram M, Dornfeld L. Atherosclerosis 2001 Sep;158(1):195-8.

Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. Kaplan M, Hayek T, Raz A, Coleman R, Dornfeld L, Vaya J, Aviram M. J Nutr 2001 Aug;131(8):2082-9.

Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Aviram M, Dornfield L.. Atheroclerosis 2001;158:195– 8.

Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. Gil MI, Tomas- Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. J Agric Food Chem 2000 Oct;48(10):4581-9.

Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, Hayek T, Presser D, Fuhrman B. Am J Clin Nutr 2000 May;71(5):1062-76.

Antioxidant andeicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. Schubert, S. Y.; Lansky, E. P.; Neeman, I. J. Ethnopharmacol 1999;66,11-17.

Changes in pomegranate juice pigmentation during ripening. Gil MI, Garcia-Viguera C, Arte´s F, Toma´s-Barbera´n F. J. Sci Food Agric 1995;68:77-81.

High molecular weight plant polyphenolics (tannins) as biological antioxidants. Hagerman AE, Riedl KM, Jones GA, Sovik KN, Ritchard NT, Hartfield PW, Riechel TL. J Agric Food Chem 1998;46:1887-1892.

Chemical composition of juice and seeds of pomegranate fruit. El-Nemr SE, Ismail IA, Ragab M. Nahrung 1990;7:601-606.

Anthocyanins of pomegranate, Punica granatum. Du CT, Wang PL, Francis FJ. J Food Sci 1975;40:417-418.